Status update

Just spent the afternoon working out next month’s budget down to the estimated dollar amount we will have available by day. This is the way I handled our budget a decade ago. Two years ago I couldn’t even balance the bank account, let alone think ahead more than a day or two. The epilepsy recovery is coming along nicely. On the downside I can’t safely write more than a couple paragraphs, and multi-tasking makes my brain fritz and spark and sputter. But I’m not complaining. This is heaven.

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If you imagine each synapse as a door to another room….

(from an email)

Brain tissue is a problem, but new brain pathways do spring up. Also, the current research seems to indicate that music thinking is a precursor to language, so it’s deeply embedded.

Well, those new synaptic pathways are also a problem for epileptics, as synapses connect in ways they shouldn’t and rerouting around synapses that should be connecting, thereby sundering the neuronal pathways to parts of the brain. It’s as if a neuron that had one hundred possible connections now has only five possible connections. If you imagine each synapse as a door to another room, suddenly ninety-five rooms have been locked shut, and everything within them is now unavailable forever. That is the impact partial seizures have on our brains, a few neurons at a time. When you realize that entire behaviors can be the result of a handful of connected neurons, it is amazing just what can be lost with even a virtually invisible seizure. A seizure is like a power surge in an electrical system, arcing currents and burning out circuits and wires and damaging machinery. As the temporal lobe seems to be much more vulnerable to this than the frontal lobe, every time an epileptic has a partial TLE seizure, some of the pathways are sundered and information is lost forever. Most we are not aware of. It can take decades to realize things are missing, though I’m sure the vast majority we have no idea we lost at all, simply because you can’t remember what you no longer remember.

The brain is able to function the way a drummer lays down a complex web of polyrhythms.

(2014)

The plasticity of the brain defies belief…a woman born without a Cerebellum and not diagnosed till age 24. Which means that even though the genes that would normally be involved in cerebellum development were missing (actually they were there, they were just unable to perform this set of tasks), other genes were able to use other parts of the brain to perform the cerebellum’s tasks. The brain is able to function the way a drummer lays down a complex web of polyrhythms. That is, a drummer has two feet and two hands, but is able to create varying patterns by combining elements of the same hands and foot pedals striking in different but simultaneous patterns. And the brain can use the same neurons in varying patterns by making varying combinations of neurons…a neuron firing can fire off other neurons simultaneously so one neuron can be part of various chains of neurons performing various functions. It’s insanely complex.

I suspect this woman needs more fuel to keep at her peak alertness since a smaller brain means that neurons are firing more often and burning through the cells stores of potassium and manganese (which are what neurons use to spark) than a healthy brain. My wife has recovered remarkably from being without a heartbeat for four minutes, but her thinking fades if she fails to eat properly throughout the day. That’s because she lost a few million neurons when oxygen stopped being delivered to the brain, and since then her brain has recovered most of its former capabilities through plasticity–other neurons taking over. But those neurons are now being used more, which means they are firing more, which means they run low on the fuel–potassium and manganese, mostly–faster than they did prior to her heart stoppage.

A ten year old told me about this story. Brains are so cool, she said.

The brain without a cerebellum.

The brain without a cerebellum.

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Plasticity

The plasticity of the brain defies belief…a woman born without a cerebellum and not diagnosed till age 24. Which means that even though the genes that would normally be involved in cerebellum development were missing (actually they were there, they were just unable to perform this set of tasks), other genes were able to use other parts of the brain to perform the cerebellum’s tasks. The brain is able to function the way a drummer lays down a complex web of polyrhythms. That is, a drummer has two feet and two hands, but is able to create varying patterns by combining elements of the same hands and foot pedals striking in different but simultaneous patterns. And the brain can use the same neurons in varying patterns by making varying combinations of neurons…a neuron firing can fire off other neurons simultaneously so one neuron can be part of various chains of neurons performing various functions. It’s insanely complex.

Neurons firing off in real-time. From 'The dynamic mind: Stunning 3D 'glass brain' (Daily Mail)

Neurons firing off in real-time. From ‘The dynamic mind: Stunning 3D ‘glass brain’ (Daily Mail)